D1538
Sigma
1,4-Bis(acryloyl)piperazine
for electrophoresis
| Synonym: | 1,4-Di(acryloyl)piperazine, N,N′-Bis(acryloyl)piperazine, BAP, PDA, Piperazine diacrylamide |
| CAS Number: | 6342-17-2 |
| Linear Formula: | C10H14N2O2 |
| Molecular Weight: | 194.23 |
| Beilstein Registry Number: | 745431 |
| MDL number: | MFCD00077661 |
| PubChem Substance ID: | 24893477 |
Description
| Application | PDA is used as a cross-linker for polyacrylamide gels to reduce background on silver-stained gels. PDA has also been shown to increase resolution and increase gel strength. |
Properties
| grade | for electrophoresis |
| mp | 91.5-93.5 °C(lit.) |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
References
| reference | Hochstrasser, D.F., et al., Development of polyacrylamide gels that improve the separation of proteins and their detection by silver staining. Anal. Biochem. 173, 412-423, (1988) Abstract |
| Hochstrasser, D.F., Methods for increasing the resolution of two-dimensional protein electrophoresis. Anal. Biochem. 173, 424, (1988) Abstract | |
| Artoni, G., et al., Fractionation techniques in a hydro-organic enviroment. II. Acryloyl-morpholine polymers as a matrix for electrophoresis in hydro-organic solvents. Anal. Biochem. 137, 420-428, (1984) Abstract | |
| Beilstein | Beil. 23,V,1,48 |







